P7: Salutary Effects of Progesterone for Traumatic Brain Injury
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p7: salutary effects of progesterone for traumatic brain injury
the sex hormone progesterone has been shown to improve outcomes in animal models and two early-phase trials involving patients with traumatic brain injury (tbi). the aim of this clinical study was to assess the effect of progesterone on the improvement of neurologic outcome in patients with diffuse and acute tbi. a prospective, randomized, double-blind trial of progesterone was conducted in our...
متن کاملP12: Progesterone Act as Neuroprotective in Traumatic Brain Injury
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متن کاملP86: Effect of Concomitant Use of Erythropoietin and Progesterone in Traumatic Brain Injury
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملEffect of Estrogen and Progesterone on Cytokines Levels at Different Time Intervals after Traumatic Brain Injury
Introduction: Following a traumatic brain injury (TBI), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. This study examined the changes in brain concentrations of proinflammatory cytokines IL-1, IL-6, TNF-α and TGF- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post...
متن کاملVery early administration of progesterone for acute traumatic brain injury.
BACKGROUND Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Progesterone has been shown to improve neurologic outcome in multiple experimental models and two early-phase trials involving patients with TBI. METHODS We conducted a double-blind, multicenter clinical trial in which patients with severe, moderate-to-severe, or moderate acute TBI (Glasgow Coma Scale ...
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عنوان ژورنال
دوره 2 شماره 4
صفحات 57- 57
تاریخ انتشار 2014-12
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